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protein glycosylation การใช้

ประโยคมือถือ
  • A common feature of pluripotent stem cells is the specific nature of protein glycosylation of their outer membrane.
  • Protein glycosylation has long been regarded not to occur in the cytoplasmic / nuclear compartments of the cell.
  • Changes in outer membrane protein glycosylation are markers of cell states connected in some way with pluripotency and differentiation.
  • By multiple gene knockout " Physcomitrella " plants were engineered that lack plant-specific post-translational protein glycosylation.
  • The principles used for eastern blotting to detect glycans can be traced back to the use of lectins to detect protein glycosylation.
  • Nonetheless, the interest in technologies to structurally mimic protein glycosylation is an appealing application as some protein functions solely depend on the pattern of the attached glycan.
  • Protein glycosylation, particularly of pilin and flagellin, became a focus of research by several groups from about 2007, and has been shown to be important for adhesion and invasion during bacterial infection.
  • GlycArt's technology platform allowed control of protein glycosylation; the cells in which obinutuzumab is reduce the amount of fucose attached to the antibody, which in turn increases the antibody's ability to activate natural killer cells.
  • As a form of protein glycosylation, it differs from most other forms in three aspects : first, it occurs exclusively within the nuclear and cytoplasmic compartments of the cell; secondly, it is generally not elongated or modified to form more complex structures; lastly it is attached and removed multiple times in the life of a polypeptide, often cycling at rapid, different rates on different sites.